Continuous Conduction of Action Potentials by Single Myelinated Fibers of Desheathed Nerve: Types of Normal Nerve Fibers.

نویسندگان

  • R LORENTEDENO
  • V HONRUBIA
چکیده

* This investigation was supported by research grant CA-4557 from the National Cancer Institute, U.S. Public Health Service (for the Cincinnati laboratory), and USPHS grants E-1992 and C-4965 (for the Boston laboratory). 1 Huebner, R. J., W. P. Rowe, H. C. Turner, and W. T. Lane, these PROCEEDINGS, 50, 379 (1963). 2 Sabin, A. B., and M. A. Koch, these PROCEEDINGS, 50, 407 (1963). 3 Black, P. H., W. P. Rowe, H. C. Turner, and R. J. Huebner, these PROCEEDINGS, 50, 1148 (1963). 4 Shein, H. M., and J. F. Enders, these PROCEEDINGS, 48, 1164-(1962); also Enders, J. F., Harvey Lectures, in press. 6 Sabin, A. B., and M. A. Koch, these PROCEEDINGS, 52, 1131 (1964). 6 Pope, J. H., and W. P. Rowe, J. Exptl. Med., 120, 121 (1964). 7 Rapp, F., T. Kitahara, J. S. Butel, and J. L. Melnick, these PROCEEDINGS, 52, 1138 (1964).

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

[Does collagenase affect the electrophysiological parameters of nerve trunk?].

Collegenase is widely used in the process of teasing a nerve in order to perform single fiber action potential (SFAP) recordings. In this study, the effects of collagenase on nerve conduction parameters were investigated. To accomplish this, normal compound action potentials (nCAPs) were recorded from isolated frog sciatic nerve at various distances using the suction technique. Then, the same n...

متن کامل

A Comparison Through

Studies with the cathode ra.y oscillograph have shown that the fibers composing a peripheral nerve range widely in their reactivities. For instance, a large nerve, such as the sciatic, contains fibers conducting at rates varying as widely as 50 to 1 with an even wider irritability range as determined by induction shocks. But neither in this nor in other nerves is there an even numerical distrib...

متن کامل

Nerve conduction block by nitric oxide that is mediated by the axonal environment.

Conduction in rat peripheral nerve has been monitored following the stimulated release of nitric oxide (NO) from diethylamine-NONOate (DEA-NONOate). Branches of the sciatic nerve were dissected, but left otherwise intact, and propagating signals recorded externally. At levels consistent with inflammation, NO exposure resulted in a complete loss of the compound action potential. Conduction was f...

متن کامل

Hyperosmolar solutions selectively block action potentials in rat myelinated sensory fibers: implications for diabetic neuropathy.

Diabetic neuropathy is a common complication of diabetes mellitus patients. It is a wide range of abnormalities affecting proximal and distal peripheral sensory and motor nerves. Although plasma hyperosmolality is a common finding in diabetes mellitus, the effects of hyperosmolality on conduction of various sensory signal components have not been addressed in detail. Here we show that in rat do...

متن کامل

Electrophysiological, behavioral and histological characterization of paclitaxel, cisplatin, vincristine and bortezomib-induced neuropathy in C57Bl/6 mice

Polyneuropathy is a frequent and potentially severe side effect of clinical tumor chemotherapy. The goal of this study was to characterize paclitaxel-, cisplatin-, vincristine- and bortezomib-induced neuropathy in C57BL/6 mice with a comparative approach. The phenotype of the animals was evaluated at four time points with behavioral and electrophysiological tests, followed by histology. Treatme...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Proceedings of the National Academy of Sciences of the United States of America

دوره 52  شماره 

صفحات  -

تاریخ انتشار 1964